Case Studies

MiraTyper on Real Tissue

Examples and evaluations across H&E, single-cell, and spatial datasets, with the measurements and reference data shown alongside the results.

Colon Cancer • H&E

Linking H&E Tissue Patterns to Microsatellite Instability in Colon Cancer

H&E tissue from the TCGA colon cancer study
H&E tissue from the exploratory TCGA colon cancer study.
121–128
Slides, by Analysis
0.760
Spatial-model AUC
24 µm
Tile Width
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Cervical Cancer • Spatial Transcriptomics

Density, not Triad Geometry, drives Allograft Rejection Signature in Reference Cervical Cancer Slide

Triad-rich cervical tissue with CD4, CD8, and dendritic cells highlighted and immune triads circled
Triad-rich zoom from the cervical cancer case study.
717,576
Cells Analyzed
406
Triad-Anchor CD8 Cells
11.6%
Mature-TLS Fraction
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Lymph Node • Spatial Transcriptomics

MiraTyper Evaluation on Xenium 5K Human Lymph Node (708K Cells)

Detail of Figure 19 showing the T-cell marker-expression comparison
Figure 19 detail: T-cell marker-expression comparison.
708,983
Cells Evaluated
0.813
Corrected h-F1
76.5%
Better Spatial Coherence
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Pancreas • Type 2 Diabetes

MiraTyper Performance on Pancreatic Type 2 Diabetes Single-Cell Datasets

Detail of Figure 1: precision and recall versus confidence threshold for exact matches and matches within one or two ontology hops
Figure 1 detail: precision and recall across confidence thresholds.
3,974
Cells Evaluated
96.2%
Accuracy (conf ≥ 0.5)
600
Annotation Corrections
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More Case Studies Coming Soon

We're continually evaluating MiraTyper on new tissues and platforms.

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